2,3-Dichloropyrazine → HCID 20528961, compound

HRID 66734

Reaction equation

HRID 66734 reaction equation
[O-:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[Na+].[Cl:9][C:10]1[C:15](Cl)=[N:14][CH:13]=[CH:12][N:11]=1>>[Cl:9][C:10]1[C:15]([O:1][C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=2)=[N:14][CH:13]=[CH:12][N:11]=1

Participants

3

Reactant 2

HCID 785752,3-DichloropyrazineHCID 4445035Phenolate Sodium

Product 1

HCID 20528961HCID 20528961, compound

Procedure

A suspension of 0.1 mole of sodium phenoxide and 0.1 mole, 2,3-dichloropyrazine is refluxed 10-20 hours. The cooled mixture is extracted with diethyl ether, washed with cold 2 N sodium hydroxide solution, dried, and evaporated to give 2-chloro-3-phenoxypyrazine.

Workup

  1. temperatureis refluxed 10-20 hours
  2. extractionThe cooled mixture is extracted with diethyl ether
  3. washwashed with cold 2 N sodium hydroxide solution
  4. customdried
  5. customevaporated

Sources & evidence

ORD record
ord-d1e4ba00ec704ab99e6cf8689a469efc
Source dataset
uspto-grants-1982_08
Patent number
US04343802

Linked notes

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