Ethanol → 2-(3,5-Difluorophenyl)-1-(oxiran-2-yl)ethanamine

Reaction equation

[CH3:19][CH2:20][OH:21].[K+:17].[NH2:1][CH:2]([CH:3]([CH2:4][Cl:5])[OH:6])[CH2:7][c:8]1[cH:9][c:10]([F:15])[cH:11][c:12]([F:14])[cH:13]1.[OH-:16].[OH2:18]>>[NH2:1][CH:2]([CH:3]1[CH2:4][O:6]1)[CH2:7][c:8]1[cH:9][c:10]([F:15])[cH:11][c:12]([F:14])[cH:13]1

Participants

Reactant 5

HCID 702Ethanol

HCID 813Potassium Cation

HCID 961Hydroxide

HCID 962Water

HCID 225930273-Amino-1-chloro-4-(3,5-difluorophenyl)butan-2-ol

Product 1

HCID 225930292-(3,5-Difluorophenyl)-1-(oxiran-2-yl)ethanamine

Sources & evidence

ORD record: ord-a23f38bfc808412d81a41057be2ade60
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (3/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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