(5-Amino-1H-benzo[d]imidazol-2-yl)methanol → (6-{7-[3-(Pyrrolidine-1-sulfonyl)-phenyl]-pyrrolo[2,1-f][1,2,4]triazin-2-ylamino}-1H-benzoimidazol-2-yl)-methanol

HRID 668314Notes

Reaction equation

HRID 668314 reaction equation
[N:1]1([S:6](=[O:7])(=[O:8])[c:9]2[cH:10][c:11](-[c:15]3[cH:16][cH:17][c:18]4[cH:19][n:20][c:21]([OH:24])[n:22][n:23]34)[cH:12][cH:13][cH:14]2)[CH2:2][CH2:3][CH2:4][CH2:5]1.[NH2:25][c:26]1[cH:27][cH:28][c:29]2[c:30]([nH:31][c:32]([CH2:34][OH:35])[n:33]2)[cH:36]1>>[N:1]1([S:6](=[O:7])(=[O:8])[c:9]2[cH:10][c:11](-[c:15]3[cH:16][cH:17][c:18]4[cH:19][n:20][c:21]([NH:25][c:26]5[cH:27][cH:28][c:29]6[c:30]([nH:31][c:32]([CH2:34][OH:35])[n:33]6)[cH:36]5)[n:22][n:23]34)[cH:12][cH:13][cH:14]2)[CH2:2][CH2:3][CH2:4][CH2:5]1

Participants

3

Reactant 2

HCID 838521(5-Amino-1H-benzo[d]imidazol-2-yl)methanolHCID 1785273247-[3-(Pyrrolidine-1-sulfonyl)-phenyl]-pyrrolo[2,1-f][1,2,4]triazin-2-ol

Product 1

HCID 66712657(6-{7-[3-(Pyrrolidine-1-sulfonyl)-phenyl]-pyrrolo[2,1-f][1,2,4]triazin-2-ylamino}-1H-benzoimidazol-2-yl)-methanol

Sources & evidence

ORD record
ord-6cc86d4ba96e4b1dbfc3f027fd656b05
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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