Methanol → 5-Bromo-4-methoxy-6-(trifluoromethyl)pyrimidine

Reaction equation

[Br:4][c:5]1[c:6]([Cl:15])[n:7][cH:8][n:9][c:10]1[C:11]([F:12])([F:13])[F:14].[CH3:16][OH:17].[CH3:1][O-:2].[Na+:3]>>[CH3:1][O:2][c:6]1[c:5]([Br:4])[c:10]([C:11]([F:12])([F:13])[F:14])[n:9][cH:8][n:7]1

Participants

Reactant 4

HCID 887Methanol

HCID 923Sodium Ion

HCID 3826051Methoxide

HCID 115362505-Bromo-4-chloro-6-(trifluoromethyl)pyrimidine

Product 1

HCID 178628975-Bromo-4-methoxy-6-(trifluoromethyl)pyrimidine

Sources & evidence

ORD record: ord-82d52aae39de4ba58f1b0be6e22a1d2a
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (3/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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