N-Methylcyclohexylamine → 2-[3-(4-Chlorophenyl)-1,2-dimethyl-1H-indole-5-yloxy]-2-methyl-propanoic acid-N-methyl-cyclohexylamide

HRID 66913

Reaction equation

[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[C:16]3[C:11](=[CH:12][CH:13]=[C:14]([O:17][C:18]([CH3:23])([CH3:22])[C:19](O)=[O:20])[CH:15]=3)[N:10]([CH3:24])[C:9]=2[CH3:25])=[CH:4][CH:3]=1.[CH3:26][NH:27][CH:28]1[CH2:33][CH2:32][CH2:31][CH2:30][CH2:29]1>>[CH3:26][N:27]([CH:28]1[CH2:33][CH2:32][CH2:31][CH2:30][CH2:29]1)[C:19](=[O:20])[C:18]([O:17][C:14]1[CH:15]=[C:16]2[C:11](=[CH:12][CH:13]=1)[N:10]([CH3:24])[C:9]([CH3:25])=[C:8]2[C:5]1[CH:6]=[CH:7][C:2]([Cl:1])=[CH:3][CH:4]=1)([CH3:23])[CH3:22]

Participants

Reactant 2

HCID 7514N-Methylcyclohexylamine

HCID 3059432Propanoic acid, 2-((3-(4-chlorophenyl)-1,2-dimethyl-1H-indol-5-yl)oxy)-2-methyl-

Product 1

HCID 205292082-[3-(4-Chlorophenyl)-1,2-dimethyl-1H-indole-5-yloxy]-2-methyl-propanoic acid-N-methyl-cyclohexylamide

Procedure

In accordance with a procedure analogous to that of Example 130, the above compound was prepared from 2-[3-(4-chlorophenyl)-1,2-dimethyl-1H-indole-5-yloxy]-2-methyl-propanoic acid and N-methyl-cyclohexylamine.

Sources & evidence

ORD record: ord-33a4076276604227a0d83678b074a1ae
Source dataset: uspto-grants-1982_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04343811

Linked notes

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