Bicarbonate Ion → cis-1-(4-Fluoro-cyclohexyl)-pyrrolidin-2-one

HRID 674403

Reaction equation

HRID 674403 reaction equation
[CH2:14]([N:15]([S:16]([F:17])([F:18])[F:20])[CH2:19][CH3:21])[CH3:22].[Cl:28][CH2:29][Cl:30].[Na+:27].[O-:23][C:24]([OH:25])=[O:26].[OH:1][CH:2]1[CH2:3][CH2:4][CH:5]([N:8]2[C:9](=[O:13])[CH2:10][CH2:11][CH2:12]2)[CH2:6][CH2:7]1>>[CH:2]1([F:20])[CH2:3][CH2:4][CH:5]([N:8]2[C:9](=[O:13])[CH2:10][CH2:11][CH2:12]2)[CH2:6][CH2:7]1

Participants

6

Reactant 5

HCID 769Bicarbonate IonHCID 923Sodium ionHCID 6344DichloromethaneHCID 123472(Diethylamino)sulfur trifluorideHCID 592993061-(4-Hydroxycyclohexyl)pyrrolidin-2-one

Product 1

HCID 57878602cis-1-(4-Fluoro-cyclohexyl)-pyrrolidin-2-one

Sources & evidence

ORD record
ord-8866fb72609f403892d543f31f9e791b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Linked notes

Loading…