HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → (RS)-Salsolinol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | Homoveratrylamine | HCID 8421 | — |
| Reactant | Propionyl chloride | HCID 62324 | — |
| Reactant | 2-(4-Methoxy-3-methylphenyl)ethan-1-amine | HCID 6484660 | — |
| Reactant | N-Ethyl-4-methoxybenzenamine | HCID 11804947 | — |
| Product | (RS)-Salsolinol | HCID 54456 | — |
| Product | 1,6-Dimethyl-1,2,3,4-tetrahydro-isoquinolin-7-ol | HCID 22018488 | — |
| Product | 1-Ethyl-1,2,3,4-tetrahydro-isoquinolin-7-ol | HCID 22018521 | — |
Reaction Steps
Similarly, 1-ethyl-1,2,3,4-tetrahydro-isoquinolin-7-ol was prepared by the above procedures by replacing the acetic anhydride in Procedure EEE with propionyl chloride. 1-Methyl-1,2,3,4-tetrahydro-isoquinoline-6,7-diol and 1,6-dimethyl-1,2,3,4-tetrahydro-isoquinolin-7-ol were prepared by replacing the (4-methoxy-phenyl)-ethylamine in procedure EEE with 3,4-dimethoxyphenylethylamine and 3-methyl-4-methoxyphenylethylamine, respectively.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07084154B2 |
| Source dataset | uspto-grants-2006_08 |
| ORD ID | ord-e7cbb3815910472891528b46b72c15cf |
| Source note | uspto-grants-2006_08 |