3-[3-(6-Methoxy-pyridin-3-yl)-phenyl]-3-oxo-propionic acid tert-butyl ester → [2-{3-[3-(6-Methoxy-pyridin-3-yl)-phenyl]-3-oxo-propionylamino}-5-(2,2,2-trifluoro-ethoxy)-phenyl]-carbamic acid tert-butyl ester

HRID 676008

Reaction equation

HRID 676008 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][c:8]1[c:9]([NH2:20])[cH:10][cH:11][c:12]([O:14][CH2:15][C:16]([F:17])([F:18])[F:19])[cH:13]1)=[O:21].[C:22]([CH3:24])([CH3:25])([O:26][C:27](=[O:23])[CH2:28][C:29](=[O:30])[c:31]1[cH:32][c:33](-[c:37]2[cH:38][n:39][c:40]([O:43][CH3:44])[cH:41][cH:42]2)[cH:34][cH:35][cH:36]1)[CH3:45]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][c:8]1[c:9]([NH:20][C:27](=[O:26])[CH2:28][C:29](=[O:30])[c:31]2[cH:32][c:33](-[c:37]3[cH:38][n:39][c:40]([O:43][CH3:44])[cH:41][cH:42]3)[cH:34][cH:35][cH:36]2)[cH:10][cH:11][c:12]([O:14][CH2:15][C:16]([F:17])([F:18])[F:19])[cH:13]1)=[O:21]

Participants

3

Reactant 2

HCID 694866953-[3-(6-Methoxy-pyridin-3-yl)-phenyl]-3-oxo-propionic acid tert-butyl esterHCID 69487918Carbamic acid,[2-amino-5-(2,2,2-trifluoroethoxy)phenyl]-,1,1-dimethylethyl ester

Product 1

HCID 86589336[2-{3-[3-(6-Methoxy-pyridin-3-yl)-phenyl]-3-oxo-propionylamino}-5-(2,2,2-trifluoro-ethoxy)-phenyl]-carbamic acid tert-butyl ester

Sources & evidence

ORD record
ord-6b870ca805af4a2596956e5e14cc0378
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Linked notes

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