Pyridine → trans-4-(Boc-amino)cyclohexyl methanesulfonate

HRID 676375

Reaction equation

HRID 676375 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][CH:8]1[CH2:9][CH2:10][CH:11]([OH:14])[CH2:12][CH2:13]1)=[O:15].[CH3:22][S:23](=[O:24])(=[O:25])[Cl:26].[Cl:27][CH2:28][Cl:29].[cH:16]1[cH:17][cH:18][n:19][cH:20][cH:21]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][CH:8]1[CH2:9][CH2:10][CH:11]([O:14][S:23]([CH3:22])(=[O:24])=[O:25])[CH2:12][CH2:13]1)=[O:15]

Participants

5

Reactant 4

HCID 1049PyridineHCID 6344DichloromethaneHCID 31297Methanesulfonyl chlorideHCID 1514287cis-4-(tert-Butoxycarbonylamino)cyclohexanol

Product 1

HCID 21882613trans-4-(Boc-amino)cyclohexyl methanesulfonate

Sources & evidence

ORD record
ord-9f4df9d754bb4bd3a8d7094c43a811b5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Linked notes

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