2-Aminopyrimidine-5-boronic acid, pinacol ester → 2-(4-((2-(2-aminopyrimidin-5-yl)-4-morpholinothieno[3,2-d]pyrimidin-6-yl)methyl)piperazin-1-yl)-N,2-dimethylpropanamide
Reaction equation
[CH3:31][C:32]1([CH3:33])[C:34]([CH3:35])([CH3:36])[O:37][B:38]([c:39]2[cH:40][n:41][c:42]([NH2:45])[n:43][cH:44]2)[O:46]1.[Cl:1][c:2]1[n:3][c:4]([N:25]2[CH2:26][CH2:27][O:28][CH2:29][CH2:30]2)[c:5]2[c:6]([n:7]1)[cH:8][c:9]([CH2:11][N:12]1[CH2:13][CH2:14][N:15]([C:18]([C:19](=[O:20])[NH:21][CH3:22])([CH3:23])[CH3:24])[CH2:16][CH2:17]1)[s:10]2>>[c:2]1(-[c:39]2[cH:40][n:41][c:42]([NH2:45])[n:43][cH:44]2)[n:3][c:4]([N:25]2[CH2:26][CH2:27][O:28][CH2:29][CH2:30]2)[c:5]2[c:6]([n:7]1)[cH:8][c:9]([CH2:11][N:12]1[CH2:13][CH2:14][N:15]([C:18]([C:19](=[O:20])[NH:21][CH3:22])([CH3:23])[CH3:24])[CH2:16][CH2:17]1)[s:10]2Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-47e534a4e3a14c67ae81bde3d2a5a747
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)