Ethanol → 4-(3-(Dimethylamino)propoxy)aniline

Reaction equation

[CH3:19][CH2:20][OH:21].[CH3:1][N:2]([CH2:3][CH2:4][CH2:5][O:6][c:7]1[cH:8][cH:9][c:10]([N+:13]([O-:14])=[O:15])[cH:11][cH:12]1)[CH3:16].[H:17][H:18].[OH-:22].[OH-:23].[Pd+2:24]>>[CH3:1][N:2]([CH2:3][CH2:4][CH2:5][O:6][c:7]1[cH:8][cH:9][c:10]([NH2:13])[cH:11][cH:12]1)[CH3:16]

Participants

Reactant 5

HCID 702Ethanol

HCID 961Hydroxide2×

HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)

HCID 10353575N,N-dimethyl-3-(4-nitrophenoxy)propan-1-amine

HCID 178418361HCID 178418361, compound

Product 1

HCID 100584694-(3-(Dimethylamino)propoxy)aniline

Sources & evidence

ORD record: ord-80061f3e05494f5d84e1afb30f9ade3f
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (3/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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