Dimethyl Sulfoxide → 2-Cyanomethyl-8-(2,6-dimethylbenzylamino)-3-methylimidazo[1,2-a]pyridine

Reaction equation

[CH2:30]([Cl:31])[Cl:32].[CH3:26][S:27](=[O:28])[CH3:29].[Cl:1][CH2:2][c:3]1[n:4][c:5]2[n:6]([cH:7][cH:8][cH:9][c:10]2[NH:11][CH2:12][c:13]2[c:14]([CH3:20])[cH:15][cH:16][cH:17][c:18]2[CH3:19])[c:21]1[CH3:22].[K:23][C:24]#[N:25].[OH2:33]>>[CH2:2]([c:3]1[n:4][c:5]2[n:6]([cH:7][cH:8][cH:9][c:10]2[NH:11][CH2:12][c:13]2[c:14]([CH3:20])[cH:15][cH:16][cH:17][c:18]2[CH3:19])[c:21]1[CH3:22])[C:24]#[N:25]

Participants

Reactant 5

HCID 679Dimethyl Sulfoxide

HCID 962Water

HCID 6344Dichloromethane

HCID 226726282-Chloromethyl-8-(2,6-dimethylbenzylamino)-3-methylimidazo[1,2-a]pyridine

HCID 178511842HCID 178511842, compound

Product 1

HCID 226725662-Cyanomethyl-8-(2,6-dimethylbenzylamino)-3-methylimidazo[1,2-a]pyridine

Sources & evidence

ORD record: ord-ddc46c6e31254d8ebabb36495dd43f7a
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (3/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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