Methanesulfonyl chloride → N-[3-(2-Chloro-pyrimidin-4-yl)-benzyl]-N-(2-pyridin-3-yl-ethyl)-methanesulfonamide

Reaction equation

[CH3:24][S:25]([Cl:26])(=[O:27])=[O:28].[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6](-[c:8]2[cH:9][c:10]([CH2:11][NH:12][CH2:13][CH2:14][c:15]3[cH:16][n:17][cH:18][cH:19][cH:20]3)[cH:21][cH:22][cH:23]2)[n:7]1>>[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6](-[c:8]2[cH:9][c:10]([CH2:11][N:12]([CH2:13][CH2:14][c:15]3[cH:16][n:17][cH:18][cH:19][cH:20]3)[S:25]([CH3:24])(=[O:27])=[O:28])[cH:21][cH:22][cH:23]2)[n:7]1

Participants

Reactant 2

HCID 31297Methanesulfonyl chloride

HCID 86603256N-(3-(2-chloropyrimidin-4-yl)benzyl)-2-(pyridine-3-yl)ethanamine

Product 1

HCID 86603255N-[3-(2-Chloro-pyrimidin-4-yl)-benzyl]-N-(2-pyridin-3-yl-ethyl)-methanesulfonamide

Sources & evidence

ORD record: ord-f0d8072a6fd24e2789e6bb0e40f65113
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (3/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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