HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,4-Dichlorobenzene → 2-Bromo-1,4-dichlorobenzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,4-Dichlorobenzene | HCID 4685 | — |
| Reactant | Bromobenzene | HCID 7961 | — |
| Reactant | Aluminum(III) Chloride | HCID 6451240 | — |
| Reactant | 1,2-dibromo-3,4-dichlorobenzene | HCID 14029663 | — |
| Catalyst | Iron | HCID 23925 | — |
| Product | 2-Bromo-1,4-dichlorobenzene | HCID 15033 | — |
| Product | 4-Bromo-1,2-dichlorobenzene | HCID 29013 | — |
| Product | 1-Bromo-2,4-dichlorobenzene | HCID 70947 | — |
Reaction Steps
The o-, m- or p-dichlorobenzenes or mixture thereof which is used as intermediates for syntheses of various organic compounds is brominated at 0° to 100° C. in the presence of aluminum chloride, ferric chloride or iron powder. The bromobenzene is chlorinated in the same condition. The dichlorobenzene is reacted with the dibromodichlorobenzene in the presence of an aluminum halide for 1 to 5 hours. In these methods, 1-bromo-2,4-dichlorobenzene, 1-bromo-2,5-dichlorobenzene, and 1-bromo-3,4-dichlorobenzene etc. can be obtained in high yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04347390 |
| Source dataset | uspto-grants-1982_08 |
| ORD ID | ord-12b808519d014a45884e6fff12f972d8 |
| Source note | uspto-grants-1982_08 |