4-(3,4-Dichlorophenoxy)piperidine → Quinoline-4-carboxylic acid trans(4-{2-[4-(3,4-dichloro-phenoxy)-piperidin-1-yl]-ethyl}-cyclohexyl)-amide

HRID 680779

Reaction equation

HRID 680779 reaction equation
[Cl:23][c:24]1[cH:25][c:26]([O:27][CH:28]2[CH2:29][CH2:30][NH:31][CH2:32][CH2:33]2)[cH:34][cH:35][c:36]1[Cl:37].[O:1]=[CH:2][CH2:3][CH:4]1[CH2:5][CH2:6][CH:7]([NH:10][C:11](=[O:12])[c:13]2[cH:14][cH:15][n:16][c:17]3[cH:18][cH:19][cH:20][cH:21][c:22]23)[CH2:8][CH2:9]1>>[CH2:2]([CH2:3][CH:4]1[CH2:5][CH2:6][CH:7]([NH:10][C:11](=[O:12])[c:13]2[cH:14][cH:15][n:16][c:17]3[cH:18][cH:19][cH:20][cH:21][c:22]23)[CH2:8][CH2:9]1)[N:31]1[CH2:30][CH2:29][CH:28]([O:27][c:26]2[cH:25][c:24]([Cl:23])[c:36]([Cl:37])[cH:35][cH:34]2)[CH2:33][CH2:32]1

Participants

3

Reactant 2

HCID 37320424-(3,4-Dichlorophenoxy)piperidineHCID 59464620Quinoline-4-carboxylic acid trans-[4-(2-oxo-ethyl)-cyclohexyl]-amide

Product 1

HCID 24954400Quinoline-4-carboxylic acid trans(4-{2-[4-(3,4-dichloro-phenoxy)-piperidin-1-yl]-ethyl}-cyclohexyl)-amide

Sources & evidence

ORD record
ord-6e926b0d591d47ebb5b5275e438aa8d4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Linked notes

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