HuagongsheHuagongshe Chemistry Print Report · For research reference only
Mannitol → Morphine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Mannitol | HCID 6251 | — |
| Reactant | Sulfuric acid--17-methyl-7,8-didehydro-4,5-epoxymorphinan-3,6-diol--water (1/1/5) | HCID 6436139 | — |
| Product | Morphine | HCID 5288826 | — |
Reaction Steps
The active plug comprised: PoloXamer 188, PEO 300 000, Morphine Sulphate pentahydrate and Mannitol, which were mixed. Afterwards the powder mixture fed to the injection moulding machine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08821928B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-84cac8d0701c40cc88768422185e2b4c |
| Source note | uspto-grants-2014_09 |