(3-Amino-2',3'-difluoro-biphenyl-4-yl)-carbamic acid tert.-butyl ester → {2',3'-Difluoro-3-[3-oxo-3-(3-[1,2,3]triazol-1-yl-phenyl)-propionylamino]-biphenyl-4-yl}-carbamic acid tert.-butyl ester

HRID 682513

Reaction equation

HRID 682513 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][c:8]1[c:9]([NH2:22])[cH:10][c:11](-[c:14]2[c:15]([F:21])[c:16]([F:20])[cH:17][cH:18][cH:19]2)[cH:12][cH:13]1)=[O:23].[CH2:24]([O:26][C:27](=[O:25])[CH2:28][C:29]([c:30]1[cH:31][c:32](-[n:36]2[n:37][n:38][cH:39][cH:40]2)[cH:33][cH:34][cH:35]1)=[O:41])[CH3:42]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][c:8]1[c:9]([NH:22][C:27](=[O:26])[CH2:28][C:29]([c:30]2[cH:31][c:32](-[n:36]3[n:37][n:38][cH:39][cH:40]3)[cH:33][cH:34][cH:35]2)=[O:41])[cH:10][c:11](-[c:14]2[c:15]([F:21])[c:16]([F:20])[cH:17][cH:18][cH:19]2)[cH:12][cH:13]1)=[O:23]

Participants

3

Reactant 2

HCID 69592847(3-Amino-2',3'-difluoro-biphenyl-4-yl)-carbamic acid tert.-butyl esterHCID 695928683-Oxo-3-(3-[1,2,3)triazol-1-yl-phenyl)-propionic acid ethyl ester

Product 1

HCID 86588079{2',3'-Difluoro-3-[3-oxo-3-(3-[1,2,3]triazol-1-yl-phenyl)-propionylamino]-biphenyl-4-yl}-carbamic acid tert.-butyl ester

Sources & evidence

ORD record
ord-e6cd5a2521cd488b8c0ba61250c6e3ce
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Linked notes

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