Diethyl 2-(hydroxymethyl)-2-phenylmalonate → 2-(2-{3-Ethoxycarbonyl-4-[(4'-trifluoromethylbiphenyl-2-carbonyl)amino]phenyl}acetoxymethyl)-2-phenylmalonic acid diethyl ester
Reaction equation
[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[cH:7][c:8]([CH2:31][C:32](=[O:33])[OH:34])[cH:9][cH:10][c:11]1[NH:12][C:13](=[O:14])[c:15]1[c:16](-[c:21]2[cH:22][cH:23][c:24]([C:27]([F:28])([F:29])[F:30])[cH:25][cH:26]2)[cH:17][cH:18][cH:19][cH:20]1.[CH2:35]([CH3:36])[O:37][C:38]([C:39]([C:40](=[O:41])[O:42][CH2:43][CH3:44])([c:45]1[cH:46][cH:47][cH:48][cH:49][cH:50]1)[CH2:51][OH:52])=[O:53]>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[cH:7][c:8]([CH2:31][C:32]([O:33][CH2:51][C:39]([C:38]([O:37][CH2:35][CH3:36])=[O:53])([C:40](=[O:41])[O:42][CH2:43][CH3:44])[c:45]2[cH:46][cH:47][cH:48][cH:49][cH:50]2)=[O:34])[cH:9][cH:10][c:11]1[NH:12][C:13](=[O:14])[c:15]1[c:16](-[c:21]2[cH:22][cH:23][c:24]([C:27]([F:28])([F:29])[F:30])[cH:25][cH:26]2)[cH:17][cH:18][cH:19][cH:20]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-8d5b3ba13c3f48d3b7a9dd58b84cfc2f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)