3,5-Difluorobenzoyl chloride → 3,5-Difluoro-N-({1-[4-hydroxy-4-(6-methoxy-pyridin-3-yl)-cyclohexyl]-azetidin-3-ylcarbamoyl}-methyl)-benzamide
Reaction equation
[F:25][c:26]1[cH:27][c:28]([C:29](=[O:30])[Cl:31])[cH:32][c:33]([F:35])[cH:34]1.[NH2:1][CH2:2][C:3](=[O:4])[NH:5][CH:6]1[CH2:7][N:8]([CH:10]2[CH2:11][CH2:12][C:13]([c:16]3[cH:17][n:18][c:19]([O:22][CH3:23])[cH:20][cH:21]3)([OH:24])[CH2:14][CH2:15]2)[CH2:9]1>>[NH:1]([CH2:2][C:3](=[O:4])[NH:5][CH:6]1[CH2:7][N:8]([CH:10]2[CH2:11][CH2:12][C:13]([c:16]3[cH:17][n:18][c:19]([O:22][CH3:23])[cH:20][cH:21]3)([OH:24])[CH2:14][CH2:15]2)[CH2:9]1)[C:29]([c:28]1[cH:27][c:26]([F:25])[cH:34][c:33]([F:35])[cH:32]1)=[O:30]Participants
3
Sources & evidence
- ORD record
- ord-03e2d20679724764b0bb83c42d8a7876
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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