Monomethyl terephthalate → Methyl 4-{[(4-hydroxybutyl)amino]carbonyl}benzoate

HRID 68646

Reaction equation

HRID 68646 reaction equation
[NH2:1][CH2:2][CH2:3][CH2:4][CH2:5][OH:6].[CH3:7][O:8][C:9]([C:11]1[CH:19]=[CH:18][C:14]([C:15](O)=[O:16])=[CH:13][CH:12]=1)=[O:10]>>[OH:6][CH2:5][CH2:4][CH2:3][CH2:2][NH:1][C:15]([C:14]1[CH:18]=[CH:19][C:11]([C:9]([O:8][CH3:7])=[O:10])=[CH:12][CH:13]=1)=[O:16]

Participants

3

Reactant 2

HCID 15513Monomethyl terephthalateHCID 258684-Amino-1-butanol

Product 1

HCID 4381083Methyl 4-{[(4-hydroxybutyl)amino]carbonyl}benzoate

Procedure

The same procedure as a series of reactions of Example 17 was carried out, except that 4-amino-1-butanol was used in place of the compound 16 and 4-(methoxycarbonyl)benzoic acid was used in place of 1H-imidazole-2-carboxylic acid, to obtain the title compound having the following physical properties.

Sources & evidence

ORD record
ord-6f66d895942e4a5bb2ba82c0bc8bff89
Source dataset
uspto-grants-2014_09
Patent number
US08822459B2

Linked notes

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