Hydrogen chloride-ethyl acetate → 3-ethyl-1-phenyl-1H-indazol-6-amine hydrochloride

Participants

Reaction Steps

Into a 100-mL round-bottom flask, was placed 3-ethyl-1-phenyl-1H-indazol-6-amine (190 mg, 0.80 mmol, 1.00 equiv), hydrogen chloride/EtOAc (30 mL). The resulting solution was stirred for 30 min at room temperature. The resulting mixture was concentrated under vacuum. The resulting mixture was washed with diethyl ether (1×50 mL). The solids were collected by filtration to yield 3-ethyl-1-phenyl-1H-indazol-6-amine hydrochloride as a white solid.

Provenance & Evidence