1,4-Dioxa-8-azaspiro(4.5)decane → HCID 68290246, compound

HRID 68792

Reaction equation

HRID 68792 reaction equation
[O:1]1[C:5]2([CH2:10][CH2:9][NH:8][CH2:7][CH2:6]2)[O:4][CH2:3][CH2:2]1.Cl[C:12]1[N:17]=[CH:16][C:15]([CH2:18][CH3:19])=[CH:14][N:13]=1>>[CH2:18]([C:15]1[CH:14]=[N:13][C:12]([N:8]2[CH2:9][CH2:10][C:5]3([O:4][CH2:3][CH2:2][O:1]3)[CH2:6][CH2:7]2)=[N:17][CH:16]=1)[CH3:19]

Participants

3

Reactant 2

HCID 674351,4-Dioxa-8-azaspiro(4.5)decaneHCID 35727632-Chloro-5-ethylpyrimidine

Product 1

HCID 68290246HCID 68290246, compound

Procedure

The title compound is prepared from 1,4-dioxa-8-azaspiro[4.5]decane and 2-chloro-5-ethyl-pyrimidine following a procedure analogous to that described for Intermediate 61.

Sources & evidence

ORD record
ord-145d4d5423a04b1f8263d4e3007f479e
Source dataset
uspto-grants-2014_09
Patent number
US08822471B2

Linked notes

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