Methanol → N-[2-[4-[(5-chlorothiophen-2-yl)methoxy]-3-methoxyphenyl]ethyl]-2-(ethylsulfonylamino)-3-methylbutanamide

HRID 688992

Reaction equation

HRID 688992 reaction equation
[CH3:33][O-:34].[CH3:38][OH:39].[Cl:25][c:26]1[s:27][c:28]([CH2:31][Cl:32])[cH:29][cH:30]1.[Na+:35].[Na+:37].[OH-:36].[OH:1][c:2]1[c:3]([O:23][CH3:24])[cH:4][c:5]([CH2:8][CH2:9][NH:10][C:11]([CH:12]([CH:13]([CH3:14])[CH3:15])[NH:16][S:17](=[O:18])(=[O:19])[CH2:20][CH3:21])=[O:22])[cH:6][cH:7]1>>[O:1]([c:2]1[c:3]([O:23][CH3:24])[cH:4][c:5]([CH2:8][CH2:9][NH:10][C:11]([CH:12]([CH:13]([CH3:14])[CH3:15])[NH:16][S:17](=[O:18])(=[O:19])[CH2:20][CH3:21])=[O:22])[cH:6][cH:7]1)[CH2:31][c:28]1[s:27][c:26]([Cl:25])[cH:30][cH:29]1

Participants

7

Reactant 6

HCID 887MethanolHCID 923Sodium ion2×HCID 961HydroxideHCID 5830792-Chloro-5-(chloromethyl)thiopheneHCID 3826051MethoxideHCID 186201972-(ethylsulfonylamino)-N-[2-(4-hydroxy-3-methoxyphenyl)ethyl]-3-methylbutanamide

Product 1

HCID 20678696N-[2-[4-[(5-chlorothiophen-2-yl)methoxy]-3-methoxyphenyl]ethyl]-2-(ethylsulfonylamino)-3-methylbutanamide

Sources & evidence

ORD record
ord-99df27c8ba244b4ba4a7a08ef2e40a74
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Linked notes

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