Dimethyl Sulfoxide → [6-(4-Fluoro-phenyl)-thieno[3,2-d]pyrimidin-4-yl]-(1H-indol-5-yl)-amine

Reaction equation

[Br:11][c:12]1[cH:13][c:14]2[n:15][cH:16][n:17][c:18]([NH:21][c:22]3[cH:23][c:24]4[cH:25][cH:26][nH:27][c:28]4[cH:29][cH:30]3)[c:19]2[s:20]1.[CH3:31][S:32]([CH3:33])=[O:34].[F:1][c:2]1[cH:3][cH:4][c:5]([B:8]([OH:9])[OH:10])[cH:6][cH:7]1>>[F:1][c:2]1[cH:3][cH:4][c:5](-[c:12]2[cH:13][c:14]3[n:15][cH:16][n:17][c:18]([NH:21][c:22]4[cH:23][c:24]5[cH:25][cH:26][nH:27][c:28]5[cH:29][cH:30]4)[c:19]3[s:20]2)[cH:6][cH:7]1

Participants

Reactant 3

HCID 679Dimethyl Sulfoxide

HCID 2856454-Fluorophenylboronic acid

HCID 18383051(6-Bromo-thieno[3,2-d]pyrimidin-4-yl)-(1H-indol-5-yl)-amine

Product 1

HCID 9906899[6-(4-Fluoro-phenyl)-thieno[3,2-d]pyrimidin-4-yl]-(1H-indol-5-yl)-amine

Sources & evidence

ORD record: ord-e760e3160ade48de9886b402ed13b042
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (3/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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