2-Chloroethylamine → [1-(2-Amino-ethyl)-6-chloro-1H-indol-3-yl]-[4-(2-fluoro-phenyl)-piperazin-1-yl]-methanone

Reaction equation

[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([C:11](=[O:12])[N:13]3[CH2:14][CH2:15][N:16]([c:19]4[c:20]([F:25])[cH:21][cH:22][cH:23][cH:24]4)[CH2:17][CH2:18]3)[cH:7][nH:8][c:9]2[cH:10]1.[Cl:26][CH2:27][CH2:28][NH2:29]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([C:11](=[O:12])[N:13]3[CH2:14][CH2:15][N:16]([c:19]4[c:20]([F:25])[cH:21][cH:22][cH:23][cH:24]4)[CH2:17][CH2:18]3)[cH:7][n:8]([CH2:27][CH2:28][NH2:29])[c:9]2[cH:10]1

Participants

Reactant 2

HCID 133692-Chloroethylamine

HCID 16061731(6-Chloro-1H-indol-3-yl)[4-(2-fluorophenyl)piperazin-1-yl]methanone

Product 1

HCID 16061732[1-(2-Amino-ethyl)-6-chloro-1H-indol-3-yl]-[4-(2-fluoro-phenyl)-piperazin-1-yl]-methanone

Sources & evidence

ORD record: ord-9a7804119c0a45eebff348625eb530fd
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (3/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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