2-Methyl-5-(trifluoromethoxy)benzoic acid → 5-(7-Methoxy-3H-spiro[1-benzofuran-2,1'-cyclopentan]-4-yl)-4,4-dimethyl-2-(1-{[2-methyl-5-(trifluoromethoxy)phenyl]carbonyl}piperidin-4-yl)-2,4-dihydro-3H-pyrazol-3-one

Reaction equation

[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([C:16]2=[N:20][N:19]([CH:21]3[CH2:22][CH2:23][NH:24][CH2:25][CH2:26]3)[C:18](=[O:27])[C:17]2([CH3:28])[CH3:29])[c:7]2[c:11]1[O:10][C:9]1([CH2:8]2)[CH2:12][CH2:13][CH2:14][CH2:15]1.[CH3:30][c:31]1[c:32]([C:33](=[O:34])[OH:35])[cH:36][c:37]([O:40][C:41]([F:42])([F:43])[F:44])[cH:38][cH:39]1>>[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([C:16]2=[N:20][N:19]([CH:21]3[CH2:22][CH2:23][N:24]([C:33]([c:32]4[c:31]([CH3:30])[cH:39][cH:38][c:37]([O:40][C:41]([F:42])([F:43])[F:44])[cH:36]4)=[O:34])[CH2:25][CH2:26]3)[C:18](=[O:27])[C:17]2([CH3:28])[CH3:29])[c:7]2[c:11]1[O:10][C:9]1([CH2:8]2)[CH2:12][CH2:13][CH2:14][CH2:15]1