6-Bromopyridine-3-carbonitrile → 6-[4-[1-[6-(4-Fluorophenyl)-6-(2-hydroxy-2-methylpropyl)-2-oxo-1,3-oxazinan-3-yl]ethyl]phenyl]pyridine-3-carbonitrile

HRID 691305

Reaction equation

HRID 691305 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([CH:8]([CH3:9])[N:10]2[C:11](=[O:28])[O:12][C:13]([CH2:16][C:17]([CH3:18])([CH3:19])[OH:20])([c:21]3[cH:22][cH:23][c:24]([F:27])[cH:25][cH:26]3)[CH2:14][CH2:15]2)[cH:6][cH:7]1.[Br:29][c:30]1[n:31][cH:32][c:33]([C:36]#[N:37])[cH:34][cH:35]1>>[c:2]1(-[c:30]2[n:31][cH:32][c:33]([C:36]#[N:37])[cH:34][cH:35]2)[cH:3][cH:4][c:5]([CH:8]([CH3:9])[N:10]2[C:11](=[O:28])[O:12][C:13]([CH2:16][C:17]([CH3:18])([CH3:19])[OH:20])([c:21]3[cH:22][cH:23][c:24]([F:27])[cH:25][cH:26]3)[CH2:14][CH2:15]2)[cH:6][cH:7]1

Participants

3

Reactant 2

HCID 50057186-Bromopyridine-3-carbonitrileHCID 723443073-[1-(4-Bromophenyl)ethyl]-6-(4-fluorophenyl)-6-(2-hydroxy-2-methylpropyl)-1,3-oxazinan-2-one

Product 1

HCID 913512586-[4-[1-[6-(4-Fluorophenyl)-6-(2-hydroxy-2-methylpropyl)-2-oxo-1,3-oxazinan-3-yl]ethyl]phenyl]pyridine-3-carbonitrile

Sources & evidence

ORD record
ord-b62c050d2277415bbd32b324c3106ba3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Linked notes

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