HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Amino-3-chloropyridazine → [2-(6-Chloro-3-pyridazinyl)-2-azavinyl]dimethylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Amino-3-chloropyridazine | HCID 21643 | — |
| Reactant | Dimethylformamide dimethyl acetal | HCID 78373 | — |
| Product | [2-(6-Chloro-3-pyridazinyl)-2-azavinyl]dimethylamine | HCID 6802247 | — |
Reaction Steps
A mixture of 3-amino-6-chloropyridazine (6.39 g, 49.3 mmol) and N,N-dimethylformamide dimethyl acetal (7.67 mL, 54.3 mmol) was stirred under reflux for 75 min. Excess N,N-dimethyl-formamide dimethyl acetal was removed to afford the title compound as a beige solid (tR 1.0 min (conditions 1), MH+=185).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08822468B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-b23567cd310b4b37811b6c274507ad7a |
| Source note | uspto-grants-2014_09 |