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Acetonitrile → [(3RS,4SR)-4-(3,4-dichloro-phenyl)-pyrrolidin-3-yl]-methyl-carbamic acid tert-butyl ester

HRID 691616
Notes
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Reaction equation

HRID 691616 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([N:7]([CH3:8])[CH:9]1[CH2:10][N:11]([CH2:22][c:23]2[cH:24][cH:25][cH:26][cH:27][cH:28]2)[CH2:12][CH:13]1[c:14]1[cH:15][c:16]([Cl:21])[c:17]([Cl:20])[cH:18][cH:19]1)=[O:29].[CH3:39][C:40]#[N:41].[Cl:30][C:31]([O:32][CH2:33][C:34]([Cl:35])([Cl:36])[Cl:37])=[O:38]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([N:7]([CH3:8])[CH:9]1[CH2:10][NH:11][CH2:12][CH:13]1[c:14]1[cH:15][c:16]([Cl:21])[c:17]([Cl:20])[cH:18][cH:19]1)=[O:29]
ParticipantsSources & evidenceReaction notes

Participants

4

Reactant 3

HCID 6342AcetonitrileHCID 870632,2,2-Trichloroethyl chloroformateHCID 67025859[(3RS,4SR)-1-Benzyl-4-(3,4-dichloro-phenyl)-pyrrolidin-3-yl]-methyl-carbamic acid tert-butyl ester

Product 1

HCID 67025572[(3RS,4SR)-4-(3,4-dichloro-phenyl)-pyrrolidin-3-yl]-methyl-carbamic acid tert-butyl ester

Sources & evidence

ORD record
ord-0b4cf08464b9437e896f898fb8ea7251
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)
On this pageParticipantsSources & evidenceReaction notes
DOI
10.1039/C8SC04228D

Reaction notes

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