5-Cyanopyridine-2-carboxylic acid → N-[3-(2-amino-5,5-difluoro-4-methyl-6H-1,3-oxazin-4-yl)-4-chlorophenyl]-5-cyanopyridine-2-carboxamide
Reaction equation
[C:19](#[N:20])[c:21]1[cH:22][cH:23][c:24]([C:27](=[O:28])[OH:29])[n:25][cH:26]1.[NH2:1][c:2]1[cH:3][cH:4][c:5]([Cl:18])[c:6]([C:8]2([CH3:17])[N:9]=[C:10]([NH2:16])[O:11][CH2:12][C:13]2([F:14])[F:15])[cH:7]1>>[NH:1]([c:2]1[cH:3][cH:4][c:5]([Cl:18])[c:6]([C:8]2([CH3:17])[N:9]=[C:10]([NH2:16])[O:11][CH2:12][C:13]2([F:14])[F:15])[cH:7]1)[C:27]([c:24]1[cH:23][cH:22][c:21]([C:19]#[N:20])[cH:26][n:25]1)=[O:28]Participants
3
Sources & evidence
- ORD record
- ord-d101bbf524ae49e8812df9818106a2e8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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