HuagongsheHuagongshe Chemistry Print Report · For research reference only
(3R)-(+)-3-(Dimethylamino)pyrrolidine → 6-Butoxy-2-[4-((R)-3-dimethylamino-pyrrolidin-1-yl)-phenyl]-3,4-dihydro-2H-isoquinolin-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (3R)-(+)-3-(Dimethylamino)pyrrolidine | HCID 2758521 | — |
| Reactant | 2-(4-bromophenyl)-6-butoxy-3,4-dihydro-2H-isoquinolin-1-one | HCID 68991115 | — |
| Product | 6-Butoxy-2-[4-((R)-3-dimethylamino-pyrrolidin-1-yl)-phenyl]-3,4-dihydro-2H-isoquinolin-1-one | HCID 57916728 | — |
Reaction Steps
According to Method R, 2-(4-bromophenyl)-6-butoxy-3,4-dihydro-2H-isoquinolin-1-one was reacted with dimethyl-(R)-pyrrolidin-3-yl-amine. In this way the product was obtained with molecular weight 407.56 (C25H33N3O2); MS (ESI): 408 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08822495B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-6ce94083da4b4bdb958278a383b4a0fc |
| Source note | uspto-grants-2014_09 |