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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 6950Generated: October 25, 2026

1-[2-(3-Methyl-2-nitrophenoxy)-ethyl]-pyrrolidine → 1h-Indole,7-[2-(1-pyrrolidinyl)ethoxy]-

https://huagongshe.com/reaction/6950

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-[2-(3-Methyl-2-nitrophenoxy)-ethyl]-pyrrolidineHCID 11601260—
Reactant[2-(1H-indol-7-yloxy)-ethyl]-dimethyl-amineHCID 22019395—
ReactantDimethyl-[2-(3-methyl-2-nitro-phenoxy)-ethyl]-amineHCID 22019404—
Product1h-Indole,7-[2-(1-pyrrolidinyl)ethoxy]-HCID 11564877—

Reaction Steps

The following compound was prepared in a similar fashion, starting with dimethyl-[2-(3-methyl-2-nitro-phenoxy)-ethyl]-amine rather than 1-[2-(3-methyl-2-nitrophenoxy)-ethyl]-pyrrolidine: [2-(1H-indol-7-yloxy)-ethyl]-dimethyl-amine (69%), MS: 205 (M+H)+

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07084169B2
Source datasetuspto-grants-2006_08
ORD IDord-d630b16d159d461ab24d52bd054d2105
Source noteuspto-grants-2006_08