(2-Amino-5-dimethylamino-4-fluoro-phenyl)-carbamic acid tert.-butyl ester → (RS)-[5-Dimethylamino-4-fluoro-2-(3-oxo-3-{3-[3-(tetrahydro-pyran-2-yloxymethyl)-isoxazol-5-yl]-phenyl}-propionylamino)-phenyl]-carbamic acid tert.-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][c:8]1[c:9]([NH2:18])[cH:10][c:11]([F:17])[c:12]([N:14]([CH3:15])[CH3:16])[cH:13]1)=[O:19].[C:20]([CH3:22])([CH3:23])([O:24][C:25](=[O:21])[CH2:26][C:27]([c:28]1[cH:29][c:30](-[c:34]2[cH:35][c:36]([CH2:39][O:40][CH:41]3[O:42][CH2:43][CH2:44][CH2:45][CH2:46]3)[n:37][o:38]2)[cH:31][cH:32][cH:33]1)=[O:47])[CH3:48]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][c:8]1[c:9]([NH:18][C:25](=[O:24])[CH2:26][C:27]([c:28]2[cH:29][c:30](-[c:34]3[cH:35][c:36]([CH2:39][O:40][CH:41]4[O:42][CH2:43][CH2:44][CH2:45][CH2:46]4)[n:37][o:38]3)[cH:31][cH:32][cH:33]2)=[O:47])[cH:10][c:11]([F:17])[c:12]([N:14]([CH3:15])[CH3:16])[cH:13]1)=[O:19]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-d06661700b07415fa5efa5adc50d6e06
- Source dataset