4-Bromo-3-chlorobenzoic acid → 3-Chloro-4-{4-[5-(1-ethyl-1H-indol-6-ylcarbamoyl)-pyridin-2-yl]-piperazin-1-yl}-benzoic acid

Reaction equation

[Br:27][c:28]1[c:29]([Cl:37])[cH:30][c:31]([C:32](=[O:33])[OH:34])[cH:35][cH:36]1.[C:38]([c:39]1[cH:40][c:41]([NH:42][C:43]([c:44]2[cH:45][cH:46][c:47]([N:48]3[CH2:49][CH2:50][N:51]([c:52]4[cH:53][cH:54][c:55]([C:56]([OH:57])=[O:58])[cH:59][cH:60]4)[CH2:61][CH2:62]3)[c:63]([F:64])[cH:65]2)=[O:66])[cH:67][cH:68][cH:69]1)([CH3:70])([CH3:71])[CH3:72].[CH2:1]([CH3:2])[n:3]1[cH:4][cH:5][c:6]2[cH:7][cH:8][c:9]([NH:12][C:13]([c:14]3[cH:15][n:16][c:17]([N:20]4[CH2:21][CH2:22][NH:23][CH2:24][CH2:25]4)[cH:18][cH:19]3)=[O:26])[cH:10][c:11]12>>[CH2:1]([CH3:2])[n:3]1[cH:4][cH:5][c:6]2[cH:7][cH:8][c:9]([NH:12][C:13]([c:14]3[cH:15][n:16][c:17]([N:20]4[CH2:21][CH2:22][N:23]([c:28]5[c:29]([Cl:37])[cH:30][c:31]([C:32](=[O:33])[OH:34])[cH:35][cH:36]5)[CH2:24][CH2:25]4)[cH:18][cH:19]3)=[O:26])[cH:10][c:11]12