Dichloromethane → 1-[3-Fluoro-4-(2,2,2-trifluoroacetyl)-phenyl]-3-(4-methyl-pyridin-3-yl)-imidazolidin-2-one

HRID 697722

Reaction equation

HRID 697722 reaction equation
[Cl:27][CH2:28][Cl:29].[F:1][c:2]1[cH:3][c:4]([N:14]2[C:15](=[O:26])[N:16]([c:19]3[cH:20][n:21][cH:22][cH:23][c:24]3[CH3:25])[CH2:17][CH2:18]2)[cH:5][cH:6][c:7]1[CH:8]([C:9]([F:10])([F:11])[F:12])[OH:13].[O:30]=[Mn:31]=[O:32]>>[F:1][c:2]1[cH:3][c:4]([N:14]2[C:15](=[O:26])[N:16]([c:19]3[cH:20][n:21][cH:22][cH:23][c:24]3[CH3:25])[CH2:17][CH2:18]2)[cH:5][cH:6][c:7]1[C:8]([C:9]([F:10])([F:11])[F:12])=[O:13]

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 14801Manganese dioxideHCID 596362271-[3-Fluoro-4-(2,2,2-trifluoro-1-hydroxy-ethyl)-phenyl]-3-(4-methyl-pyridin-3-yl)-imidazolidin-2-one

Product 1

HCID 596361941-[3-Fluoro-4-(2,2,2-trifluoroacetyl)-phenyl]-3-(4-methyl-pyridin-3-yl)-imidazolidin-2-one

Sources & evidence

ORD record
ord-377d87398c6c452ea813a1ed9d009d97
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Linked notes

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