(2-Chloropyridin-3-yl)boronic acid → [7-(2-Chloro-pyridin-3-yl)-pyrrolo[2,1-f][1,2,4]triazin-2-yl]-(4-morpholin-4-yl-phenyl)-amine

HRID 698716

Reaction equation

HRID 698716 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]2[cH:6][n:7][c:8]([NH:11][c:12]3[cH:13][cH:14][c:15]([N:18]4[CH2:19][CH2:20][O:21][CH2:22][CH2:23]4)[cH:16][cH:17]3)[n:9][n:10]12.[Cl:24][c:25]1[n:26][cH:27][cH:28][cH:29][c:30]1[B:31]([OH:32])[OH:33]>>[c:2]1(-[c:30]2[c:25]([Cl:24])[n:26][cH:27][cH:28][cH:29]2)[cH:3][cH:4][c:5]2[cH:6][n:7][c:8]([NH:11][c:12]3[cH:13][cH:14][c:15]([N:18]4[CH2:19][CH2:20][O:21][CH2:22][CH2:23]4)[cH:16][cH:17]3)[n:9][n:10]12

Participants

3

Reactant 2

HCID 2762704(2-Chloropyridin-3-yl)boronic acidHCID 54578326(7-Bromo-pyrrolo[2,1-f][1,2,4]triazin-2-yl)-(4-morpholin-4-yl-phenyl)-amine

Product 1

HCID 86661687[7-(2-Chloro-pyridin-3-yl)-pyrrolo[2,1-f][1,2,4]triazin-2-yl]-(4-morpholin-4-yl-phenyl)-amine

Sources & evidence

ORD record
ord-78fd3e1c309044d0a4f72085b7e12ccd
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Linked notes

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