3-(2-Ethoxycarbonyl-vinyl)-1-(4-methoxy-benzenesulfonyl)-azepane-2-carboxylic acid tert-butyl ester → 3-(2-Hydroxycarbamoyl-1-(4-methoxy-benzenesulfonyl)-azepan-3-yl)-acrylic acid ethyl ester
Reaction equation
[C:1]([CH3:3])([CH3:4])([O:5][C:6](=[O:2])[CH:8]1[N:9]([S:22](=[O:23])(=[O:24])[c:25]2[cH:26][cH:27][c:28]([O:31][CH3:32])[cH:29][cH:30]2)[CH2:10][CH2:11][CH2:12][CH2:13][CH:14]1[CH:15]=[CH:16][C:17](=[O:18])[O:19][CH2:20][CH3:21])[CH3:7].[OH:33][NH:34][C:35]([CH:36]1[CH:37]([CH2:38][O:39][C:40](=[O:41])[CH3:42])[CH2:43][CH2:44][CH2:45][CH2:46][N:47]1[S:48]([c:49]1[cH:50][cH:51][c:52]([O:53][CH3:54])[cH:55][cH:56]1)(=[O:57])=[O:58])=[O:59]>>[O:5]=[C:6]([CH:8]1[N:9]([S:22](=[O:23])(=[O:24])[c:25]2[cH:26][cH:27][c:28]([O:31][CH3:32])[cH:29][cH:30]2)[CH2:10][CH2:11][CH2:12][CH2:13][CH:14]1[CH:15]=[CH:16][C:17](=[O:18])[O:19][CH2:20][CH3:21])[NH:34][OH:33]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-f3dacc21526442e88c13f89ca1cc66b8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)