2-Bromo-N-tert-butyl-1,3-thiazole-5-carboxamide → N-tert-butyl-2-[4-[1-[6-(2-hydroxy-2-methylpropyl)-2-oxo-6-phenyl-1,3-oxazinan-3-yl]ethyl]phenyl]-1,3-thiazole-5-carboxamide

Reaction equation

[Br:36][c:37]1[s:38][c:39]([C:42](=[O:43])[NH:44][C:45]([CH3:46])([CH3:47])[CH3:48])[cH:40][n:41]1.[OH:1][C:2]([CH2:3][C:4]1([c:28]2[cH:29][cH:30][cH:31][cH:32][cH:33]2)[CH2:5][CH2:6][N:7]([CH:11]([CH3:12])[c:13]2[cH:14][cH:15][c:16]([B:19]3[O:20][C:21]([CH3:22])([CH3:23])[C:24]([CH3:25])([CH3:26])[O:27]3)[cH:17][cH:18]2)[C:8](=[O:10])[O:9]1)([CH3:34])[CH3:35]>>[OH:1][C:2]([CH2:3][C:4]1([c:28]2[cH:29][cH:30][cH:31][cH:32][cH:33]2)[CH2:5][CH2:6][N:7]([CH:11]([CH3:12])[c:13]2[cH:14][cH:15][c:16](-[c:37]3[s:38][c:39]([C:42](=[O:43])[NH:44][C:45]([CH3:46])([CH3:47])[CH3:48])[cH:40][n:41]3)[cH:17][cH:18]2)[C:8](=[O:10])[O:9]1)([CH3:34])[CH3:35]