2-methyl-N-[3-(4-piperidyl)phenyl]propanamide → N-(3-{1-[5-(3-Fluorophenyl)-5-oxopentyl]-4-piperidinyl}phenyl)-2-methylpropanamide
Reaction equation
[CH3:15][CH:16]([C:17](=[O:18])[NH:19][c:20]1[cH:21][c:22]([CH:26]2[CH2:27][CH2:28][NH:29][CH2:30][CH2:31]2)[cH:23][cH:24][cH:25]1)[CH3:32].[Cl:1][CH2:2][CH2:3][CH2:4][CH2:5][C:6](=[O:7])[c:8]1[cH:9][c:10]([F:14])[cH:11][cH:12][cH:13]1>>[CH2:2]([CH2:3][CH2:4][CH2:5][C:6](=[O:7])[c:8]1[cH:9][c:10]([F:14])[cH:11][cH:12][cH:13]1)[N:29]1[CH2:28][CH2:27][CH:26]([c:22]2[cH:21][c:20]([NH:19][C:17]([CH:16]([CH3:15])[CH3:32])=[O:18])[cH:25][cH:24][cH:23]2)[CH2:31][CH2:30]1Participants
3
Sources & evidence
- ORD record
- ord-889b917faae8440abbcf172d1550c177
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
Loading…