Dimethylamine → N-{4-[(3-iodophenyl)amino]quinazoline-6-yl}-4-(dimethylamino)-2-butenamide
Reaction equation
[Br:20][C:21](=[CH:22][CH3:23])[C:24]([OH:25])=[O:26].[CH3:27][NH:28][CH3:29].[Cl:30][c:31]1[cH:32][c:33]([NH:34][c:35]2[c:36]3[c:37]([cH:38][cH:39][c:40]([NH:41][C:51]([CH:52]=[CH:53][CH2:54][N:55]([CH3:56])[CH3:57])=[O:58])[cH:42]3)[n:43][cH:44][n:45]2)[c:46]([F:47])[cH:48][c:49]1[Cl:50].[I:1][c:2]1[cH:3][c:4]([NH:8][c:9]2[n:10][cH:11][n:12][c:13]3[cH:14][cH:15][c:16]([NH2:19])[cH:17][c:18]23)[cH:5][cH:6][cH:7]1>>[I:1][c:2]1[cH:3][c:4]([NH:8][c:9]2[n:10][cH:11][n:12][c:13]3[cH:14][cH:15][c:16]([NH:19][C:51]([CH:52]=[CH:53][CH2:54][N:55]([CH3:56])[CH3:57])=[O:58])[cH:17][c:18]23)[cH:5][cH:6][cH:7]1Participants
5
