HuagongsheHuagongshe Chemistry Print Report · For research reference only
p-Bromophenethylamine → 4'-(2-Aminoethyl)-3-biphenylcarboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | p-Bromophenethylamine | HCID 533915 | — |
| Reactant | (3-Carbamoylphenyl)boronic acid | HCID 2737814 | — |
| Reactant | Toluene ethanol | HCID 21863594 | — |
| Solvent | 1,2-Dimethoxyethane | HCID 8071 | — |
| Product | 4'-(2-Aminoethyl)-3-biphenylcarboxamide | HCID 58276405 | — |
Reaction Steps
The title compound was prepared from 3-(aminocarbonyl)-phenyl boronic acid and 4-bromophenethylamine according to the procedure described for intermediate I-VII-1 with the exceptions that 4:1 PhMe/EtOH was sued as organic solvent (instead of DME) and the chromatographic purification step was omitted. LC/MS (method E) 0.53 min; m/z 241 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08822518B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-d3081091b1fe44fa8a47eb45f5cae40c |
| Source note | uspto-grants-2014_09 |