1-Octyn-3-ol → 1-Cyclohexyl-2-propyn-1-one
Reaction equation
[CH:1]#[C:2][CH:3]([OH:9])[CH2:4][CH2:5][CH2:6][CH2:7][CH3:8].[CH:10]#CC(=O)CCCCC>>[CH:4]1([C:3](=[O:9])[C:2]#[CH:1])[CH2:10][CH2:8][CH2:7][CH2:6][CH2:5]1Participants
3
Procedure
In like manner, but replacing the 3-cyclohexylprop-1-yn-3-ol with oct-1-yn-3-ol, oct-1-yn-3-one was prepared. C. Similarly, but starting with other appropriate 3-hydroxy-1-alkynes, prepared as shown above, the following 3-oxo-1-alkynes are prepared:
Workup
- customwas prepared
- customprepared
- customare prepared
Sources & evidence
- ORD record
- ord-322eb0d073004a00a791422d6631c17b
- Source dataset
- uspto-grants-1991_01
- Patent number
- US04983627
Reaction notes
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