Ethanol → 8-Phthalimido-3-oxooctanoic acid ethyl ester

HRID 703658

Reaction equation

HRID 703658 reaction equation
[C:1]1(=[O:19])[N:5]([CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][C:11]([OH:13])=O)[C:4](=[O:14])[C:3]2=[CH:15][CH:16]=[CH:17][CH:18]=[C:2]12.C1([CH:23](C2CC2)[CH2:24][OH:25])CC1.[CH2:29]([OH:31])[CH3:30]>>[CH2:29]([O:31][C:24](=[O:25])[CH2:23][C:11](=[O:13])[CH2:10][CH2:9][CH2:8][CH2:7][CH2:6][N:5]1[C:1](=[O:19])[C:2]2=[CH:18][CH:17]=[CH:16][CH:15]=[C:3]2[C:4]1=[O:14])[CH3:30]

Participants

4

Reactant 3

HCID 702EthanolHCID 781851,3-Dihydro-1,3-dioxo-2H-isoindole-2-hexanoic acidHCID 107018422,2-Dicyclopropylethan-1-ol

Product 1

HCID 541971308-Phthalimido-3-oxooctanoic acid ethyl ester

Procedure

This ester is synthesized according to the process described in stage A of Example 4, but replacing the 8-phthalimido-3,6-dioxaoctanoic acid with 6-phthalimidohexanoic acid and the 2,2-dicyclopropylethanol with ethanol.

Sources & evidence

ORD record
ord-12c0d9ef8aed4f449448ba702d26a82c
Source dataset
uspto-grants-1991_01
Patent number
US04983740

Linked notes

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