1-Piperazinecarboxylic acid, ethyl ester → 1-(3-Phenylpropyl)piperazine

HRID 704378

Reaction equation

HRID 704378 reaction equation
C(O[C:4]([N:6]1[CH2:11][CH2:10][NH:9][CH2:8][CH2:7]1)=O)C.BrC[CH2:14][CH2:15][C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1>>[C:16]1([CH2:15][CH2:14][CH2:4][N:6]2[CH2:7][CH2:8][NH:9][CH2:10][CH2:11]2)[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1

Participants

3

Reactant 2

HCID 84311-Piperazinecarboxylic acid, ethyl esterHCID 12503(3-Bromopropyl)benzene

Product 1

HCID 7965341-(3-Phenylpropyl)piperazine

Procedure

1-Ethoxycarbonylpiperazine and 1-bromo-3-phenylpropane were used as the starting materials and treated in the same manner as in Reference Example 9 to give 1-(3phenylpropyl)piperazine.

Workup

  1. additiontreated in the same manner as in Reference Example 9

Sources & evidence

ORD record
ord-a8fc75438e3547a0a3348bdd65b6c5e2
Source dataset
uspto-grants-1991_01
Patent number
US04987132

Linked notes

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