N,N'-Dimethylurea → Urea, 1,1-dipropyl-3-methyl-

HRID 704462

Reaction equation

HRID 704462 reaction equation
[CH3:1][NH:2][C:3](NC)=[O:4].[CH2:7]([NH:10][CH2:11][CH2:12][CH3:13])[CH2:8][CH3:9]>C1(C(C)C)C=CC=CC=1>[CH2:7]([N:10]([CH2:11][CH2:12][CH3:13])[C:3]([NH:2][CH3:1])=[O:4])[CH2:8][CH3:9]

Participants

4

Reactant 2

HCID 7293N,N'-DimethylureaHCID 8902Dipropylamine

Product 1

HCID 215877Urea, 1,1-dipropyl-3-methyl-Yield 104.9%

Reagents, catalysts & solvents 1

HCID 7406CumeneSolvent

Conditions

Temperature
137 °C

Procedure

To a 250 ml, 3-neck flask, with an agitator and condenser were added 22.0 g (0.25 mol) of 1,3-dimethylurea, 25.3 g (0.25 mol) of dipropylamine and 100 ml of cumene. The solution was heated at reflux (about 137° C.) for about 12 hours, cooled to 100° C., and the solvent was removed using vacuum distillation to provide a residue. The residue was dried in a vacuum oven at 60° C. to provide 41.5 g of 1,1-dipropyl-3-methylurea.

Workup

  1. temperatureThe solution was heated
  2. temperaturecooled to 100° C.
  3. customthe solvent was removed
  4. distillationvacuum distillation
  5. customto provide a residue
  6. customThe residue was dried in a vacuum oven at 60° C.

Sources & evidence

ORD record
ord-0f12c8dedfff4e67b84a301384f53aff
Source dataset
uspto-grants-1991_01
Patent number
US04987233

Linked notes

Loading…