Water → 3,6-Dibromobenzene-1,2-diamine

HRID 70750

Reaction equation

HRID 70750 reaction equation
[Br:1][C:2]1[C:10]2[C:6](=[N:7]S[N:9]=2)[C:5]([Br:11])=[CH:4][CH:3]=1.[BH4-].[Na+].O>C(O)C>[Br:1][C:2]1[C:10]([NH2:9])=[C:6]([NH2:7])[C:5]([Br:11])=[CH:4][CH:3]=1

Participants

5

Reactant 3

HCID 962WaterHCID 6263614,7-Dibromo-2,1,3-benzothiadiazoleHCID 4311764Sodium borohydride

Product 1

HCID 118215323,6-Dibromobenzene-1,2-diamine

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

The specific preparation is described as follows: dissolving 4,7-dibromo-2,1,3-benzothiadiazole in organic solvent such as ethanol, adding appropriate sodium borohydride at 0° C., then raising the temperature to room temperature, stirring for 12-24 hours, distilling organic solvent of reaction product, after adding water, washing with saline water, then extracting with diethyl ether, drying with anhydrous sodium sulfate. 3,6-dibromo-1,2-diaminobenzene is obtained after solvent is rotary dried.

Workup

  1. customThe specific preparation
  2. distillationdistilling organic
  3. customsolvent of reaction product
  4. washwashing with saline water
  5. extractionextracting with diethyl ether
  6. dry with materialdrying with anhydrous sodium sulfate

Sources & evidence

ORD record
ord-869ba25368eb494f825ec82fe352d855
Source dataset
uspto-grants-2014_09
Patent number
US08822634B2

Linked notes

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