Diethyl Ether → Picolinohydrazide

Temperature

80 °C

A mixture of ethyl pyridin-2-carboxylate (90 gm) and hydrazine (60 gm) in ethanol (400 ml) was stirred at 80° C. over a period of 4 h. Solvent was evaporated and to provide a crude mass. The mass was stirred with diethyl ether and the suspension was filtered and the wet cake washed with small quantity of ethanol (50 ml) to provide title compound in 76 gm quantity (93%) as a white solid.

1. customSolvent was evaporated
2. customto provide a crude mass
3. filtrationthe suspension was filtered
4. washthe wet cake washed with small quantity of ethanol (50 ml)

ORD record

ord-d650448a01824a70a2ecd839870847ed

Source dataset

uspto-grants-2015_11

DOI

10.6084/m9.figshare.5104873.v1

Patent number

US09175031B2