4-tert-Butyl-2-nitroaniline → N-(4-tert-Butyl-2-nitrophenyl)-3-(3-oxocyclobutyl)propanamide

HRID 707667

Reaction equation

HRID 707667 reaction equation
[O:1]=[C:2]1[CH2:5][CH:4]([CH2:6][CH2:7][C:8]([OH:10])=O)[CH2:3]1.[C:11]([C:15]1[CH:21]=[CH:20][C:18]([NH2:19])=[C:17]([N+:22]([O-:24])=[O:23])[CH:16]=1)([CH3:14])([CH3:13])[CH3:12]>>[C:11]([C:15]1[CH:21]=[CH:20][C:18]([NH:19][C:8](=[O:10])[CH2:7][CH2:6][CH:4]2[CH2:3][C:2](=[O:1])[CH2:5]2)=[C:17]([N+:22]([O-:24])=[O:23])[CH:16]=1)([CH3:14])([CH3:12])[CH3:13]

Participants

3

Reactant 2

HCID 805734-tert-Butyl-2-nitroanilineHCID 677753573-(3-Oxocyclobutyl)propanoic acid

Product 1

HCID 90455940N-(4-tert-Butyl-2-nitrophenyl)-3-(3-oxocyclobutyl)propanamide

Procedure

reacting 3-(3-oxocyclobutyl)propanoic acid with 4-tert-butyl-2-nitroaniline to yield N-(4-tert-butyl-2-nitrophenyl)-3-(3-oxo-cyclobutyl)propanamide; and

Sources & evidence

ORD record
ord-5f57517340dc49ba8fb92dc5edde950e
Source dataset
uspto-grants-2015_11
Patent number
US09175032B2

Linked notes

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