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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 7078Generated: October 26, 2026

4-hydroxy-3-methoxy-N-[3-(2-phenylethynyl)phenyl]-phenylacetamide → 4-hydroxy-3-methoxy-N-[2-(2-phenylethyl)phenyl]phenylacetamide

https://huagongshe.com/reaction/7078

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-hydroxy-3-methoxy-N-[3-(2-phenylethynyl)phenyl]-phenylacetamideHCID 22019612—
Reactant4-hydroxy-3-methoxy-N-[2-(2-phenylethynyl)phenyl]-phenylacetamideHCID 22019673—
Product4-hydroxy-3-methoxy-N-[2-(2-phenylethyl)phenyl]phenylacetamideHCID 22019617—

Reaction Steps

Instead of 4-hydroxy-3-methoxy-N-[3-(2-phenylethynyl)phenyl]-phenylacetamide (the compound of Example 36) in Example 54, 4-hydroxy-3-methoxy-N-[2-(2-phenylethynyl)phenyl]phenylacetamide (the compound of Example 107) is treated in a similar manner to Example 54 to give the desired compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07084176B2
Source datasetuspto-grants-2006_08
ORD IDord-8b82934688844b438738b1ec34f7bba1
Source noteuspto-grants-2006_08