HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-hydroxy-3-methoxy-N-[3-(2-phenylethynyl)phenyl]-phenylacetamide → 4-hydroxy-3-methoxy-N-[2-[(Z)-2-phenylvinyl]phenyl]-phenylacetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-hydroxy-3-methoxy-N-[3-(2-phenylethynyl)phenyl]-phenylacetamide | HCID 22019612 | — |
| Reactant | 4-hydroxy-3-methoxy-N-[2-(2-phenylethynyl)phenyl]-phenylacetamide | HCID 22019673 | — |
| Product | 4-hydroxy-3-methoxy-N-[2-[(Z)-2-phenylvinyl]phenyl]-phenylacetamide | HCID 58679870 | — |
Reaction Steps
Instead of 4-hydroxy-3-methoxy-N-[3-(2-phenylethynyl)phenyl]-phenylacetamide (the compound of Example 36) in Example 56, 4-hydroxy-3-methoxy-N-[2-(2-phenylethynyl)phenyl]phenylacetamide (the compound of Example 107) is treated in a similar manner to Example 56 to give the desired compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07084176B2 |
| Source dataset | uspto-grants-2006_08 |
| ORD ID | ord-87e6898308db4b26a4226ae53366324d |
| Source note | uspto-grants-2006_08 |